报告题目：Same RNA sequences different phenotypes- TRM5 is a nuclear-localised tRNA guanine-N1-methyltransferase in Arabidopsis thaliana

报告时间：6月26日（星期二）下午1点半

报告地点：生物药学楼2-116

主讲人：Iain Searle

主讲人简介：Iain Searle博士于2008年获得澳大利亚昆士兰大学博士学位，随后在德国Max Planck Institute、英国John Innes Centre进行博士后研究工作；2009年起到澳大利亚国立大学成立实验室；2013年起到澳大利亚阿德莱德大学工作，目前为澳大利亚阿德莱德大学遗传与进化系系主任、教授，中澳谷类与健康联合中心主任。主讲人的研究兴趣是小RNA在植物发育及抗逆中的作用。在Science、Genes & Development 、The Plant Cell、EMBO Journal、BMC Plant Biology等期刊上发表研究论文40多篇。

联系人：梁婉琪，34205073，wqliang@sjtu.edu.cn

主办单位：生命科学技术学院植物发育与生物安全实验室

讲座简介：

We are interested in the mechanisms underlying reproductive development. Through a combination of forward and reverse genetic screens in Arabidopsis we have uncovered an essential role for RNA modifications, most likely on long RNAs, during egg and pollen cell development. We have also shown a complex landscape of long non-coding RNAs during endosperm development. Recently, we demonstrated an important role for guanine-N1-methylation on tRNAs during vegetative and reproductive growth stages in Arabidopsis. Collectively, our data is illuminating a complex and essential landscape of non-coding RNAs and RNA modifications during growth and development in plants.