SKLMM Workshop （Presentation in English）
报告题目：Complexity Generation in Fungal Natural Product Biosynthesis
报 告 人：Yi Tang Chancellor Professor
Department of Chemical and Biomolecular Engineering, UCLA
Director, NIH Predoctoral Biotechnology Training Grant
主 持 人：白林泉 教授
联 系 人：林忆杉 firstname.lastname@example.org
Nature performs challenging synthetic transformations using powerful enzymes. These enzymes are frequently found in the biosynthetic pathways of natural products, many of which have served as inspirations for generations of synthetic chemists over the last fifty years. With recent advances in our abilities to manipulate the biosynthetic pathways, many powerful enzymes have been revealed and characterized. In this talk, I will present a selection of recent work in the identification, characterization and engineering of several enzymes that catalyze difficult transformations and generate structural complexity in fungi. Examples include multifunctional P450s, Diels Alderases and enzymes that catalyze epoxide rearrangements will be covered.