Long Noncoding RNA Modulate Migration of Vascular Smooth Muscle Cells

[Release time]:2019-04-25  [Hits]:2300

Contact Information Prof.  Yingxin Qi   Email: qiyx@sjtu.edu.cn

Project Description and Objectives Long non-coding RNAs (lncRNAs) are being discovered in multiple diseases at a rapid pace. Our previous sequencing result revealed several crucial lncRNAs that may contribute to dysfunctions of vascular smooth muscle cells (VSMCs). In this project, using specific siRNA transfection, we will investigate the role of screened lncRNA, especially which locus nearby the cardiovascular genetic landmark or having binding sites with miRNA, in regulation of VMSC migration. The project will achieve the deep insights into the role of lncRNA in functions of VSMCs.
Eligibility Requirements Applicants must have a basic knowledge of molecular biology. Experience in research in cell culture would be in advantage.

Main Tasks Perform experiments, analyze experimental and write a research report. Give a research presentation: technical presentation.

     

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