Yi Xiao

Special Researcher/Tenure-track Associate Professor

  • Tel: +86-021-34208601
  • Email: yi_xiao@sjtu.edu.cn
  • Address: Xitong Building (Room C404), 800 Dongchuan RD. Minhang District, Shanghai, China

Education and Research Experience

  • 2017-Current, Associate Professor, Shanghai Jiao Tong University
  • 2010-2016, Research Scientist and Postdoc,Washington University in St. Louis, USA
  • 2008-2010, Postdoc, South China Sea Institute of Oceanology, Chinese Academy of Sciences, China
  • 2019-Current, the Editorial Board of Applied and Environmental Microbiology

Selected Publications

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    Mingtao Zhao, Xulin Hong, Abdullah, Rulin Yao, Yi Xiao. Rapid biosynthesis of phenolic glycosides and their derivatives from biomass-derived hydroxycinnamates. Green Chemistry, 23, 838-847

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    Ruilian Yao, Di Liu, Xiao Jia, Yuan Zheng, Wei Liu, Yi Xiao. CRISPR-Cas9/Cas12a biotechnology and application in bacteria. Synthetic and Systems Biotechnology. 3(3):135-149

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    Mingtao Zhao, Yankai Tao, Xiaofeng Wu, Yi Xiao. One-pot efficient biosynthesis of 4-hydroxyphenylacetic acid and its analogues from lignin-related p-coumaric and ferulic acids. ACS Sustainable Chemistry & Engineering, (10.1021/acssuschemeng.1c00993)

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    Mingtao Zhao, Yankai Tao, Xiaofeng Wu, Yi Xiao. One-pot efficient biosynthesis of 4-hydroxyphenylacetic acid and its analogues from lignin-related p-coumaric and ferulic acids. ACS Sustainable Chemistry & Engineering. 9(18):6400-6409

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    Abdullah, Pujie Wang, Tongren Han, Wei Liu, Wenting Ren, Yuehong Wu, and Yi Xiao. Adenine base editing system for Pseudomonas and prediction workflow for protein dysfunction via ABE. ACS Synthetic Biology. 11(4):1650-1657.

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    Mingtao Zhao, Ziqing Qin, Abdullah, and Yi Xiao. Construction of biocatalytic cascades for the synthesis of benzylisoquinoline alkaloids from p-coumaric acid derivatives and dopamine. Green Chemistry, 24, 3225 - 3234

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    Shun Zhang, Xiaofeng Wu, and Yi Xiao. Conversion of lignin-derived 3-methoxycatechol to the natural product purpurogallin using bacterial P450 GcoAB and laccase CueO. Applied Microbiology and Biotechnology . 106(2):593-603. 

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    Zhengzheng Jiang, Abdullah, Shun Zhang, Yuli Jiang, Rui Liu, and Yi Xiao. Development and optimization of CRISPR prime editing system in photoautotrophic cells. Molecules. 27(6):1758.

     

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    Xiao Jia, Shun Zhang, Jiawei Li, Juan Xia, Ruilian Yao, Xinqing Zhao, Bing Wu, Fengwu Bai, Yi Xiao. Engineered bacterial biofloc formation enhancing phenol removal and cell tolerance. Applied Microbiology and Biotechnology. 104(3):1187-1199

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    Yi Xiao, Christopher H. Bowen, Di Liu, Fuzhong Zhang.  Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis. Nature Chemical Biology 12, 339–344

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    Yi Xiao, Shaojie Wang, Sarah Rommelfanger, Andrea Balassy, Carlos Barba-Ostria, Pengfei Gu, Jonathan M. Galazka, Fuzhong Zhang. Developing a Cas9-based tool to engineer native plasmids in Synechocystis sp. PCC 6803. Biotechnology and Bioengineering 115(9):2305-2314.

Teaching Experiences

  • Fundamentals of natural science
  • CRISPR gene editing
  • English writing 
  • National 1000 Youth Talents Program 2018
  • National Key R&D Program of China 2019/2020
  • National Natural Science Foundation of China 2019
  • Science and Technology Commission of Shanghai Municipality 2018

Selected Grants

Students