特聘教授
Cui L., Wei X., Wang X., Bai L., Lin S., Feng Y*. A Validamycin Shunt Pathway for Valienamine Synthesis in Engineered Streptomyces hygroscopicus 5008. ACS Synth Biol., 2020, 294-303.
Deng X., Chen L., Hei M., Tian G., Feng Y*., Yang G*. Structure-guided reshaping of the acyl binding pocket of 'TesAthioesterase enhances octanoic acid production in E. coli. Metab Eng. 2020, 61:24-32.
Liu Q., Guo X., Xun G., Li Z., Chong Y., Yang L., Wang H., Zhang F., Luo S., Cui L., Zhao P., Ye X., Xu H., Lu H., Li X., Deng Z., Li K., Feng Y.* Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations. Nucleic Acids Res. ,2021, gkab274.
Huang F, Xu X.Y., Dong H., Li N., Zhong B.Z., Lu H., Liu Q., Feng Y.*. Catalytic properties and biological function of a PIWI-RE nuclease from Pseudomonas stutzeri. Bioresour. Bioprocess. 2022,9, 57.
Zheng L., Lu H., Zan B., Li S., Liu H., Liu Z., Huang.J, Liu Y, Jiang F., Liu Q.*, Feng Y., Hong L.* Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity. Nucleic Acids Res., 2022, 7529–7544.
Cui L*., Cui, A., Li Q., Yang L., Liu H., Shao W., Feng Y.*. Molecular Evolution of an Aminotransferase Based on Substrate–Enzyme Binding Energy Analysis for Efficient Valienamine Synthesis. ACS Catal. 2022, 12(21): 13703-13714.
He Y., Li S., Wang J., Yang X., Zhu J., Zhang Q., Cui L., Tan Z., Yan W., Zhang Y., Tang L., Da L*., Feng Y*. Discovery and Engineering of the l-Threonine Aldolase from Neptunomonas marine for the Efficient Synthesis of β-Hydroxy-α-amino Acids via C–C Formation. ACS Catal. 2022, 13(11): 7210-7220.
Wu Z., Liu H., Xu L., Chen H., Feng Y*. Algorithm-based Coevolution Network Identification Reveals Key Functional Residues of the α/β Hydrolase Subfamilies. FASEB J. 2020, 34(2): 1983-1995.
Sun Z., Liu Q., Qu G., Feng Y*., Reetz M*. Utility of B-Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability. Chem Rev. 2019, 119(3): 1626-1665.
讲授本科生课程：生物化学-B类（Biochemistry-Class B)
讲授研究生课程：生命科学前沿进展 (Frontier Life Science Progress)
国家重点研发计划,高值化合物生物合成体系的智能组装及高效运行（2020YFA0907700）, 2020.11-2025.10,1890万元, 项目负责人；
国家自然科学基金国际（地区）合作与交流项目，假糖类药物生物合成途径的全新构建及多重适配性机制研究 (31620103901), 2017.01-12/2021.12,243万元，项目负责人；
国家重点研发计划中美政府间合作项目, 酰基修饰药物关键酶系的分子设计与药物创新优产(2017YFE0103300)，2018.01-2019.12, 341万元, 项目负责人；
国家自然科学基金国际（地区）合作与交流项目, 工程酶级联反应的合成生物学:从脂肪酶高效合成羟基脂肪酸及内酯（31861143018）， 2019.01-2021.11, 160万元，项目负责人；
国家自然科学基金面上项目，新型Argonaute核酸酶催化特性及生物学作用机制，国家自然科学基金面上项目（32170035）,2022.01-2025.12,58万元, 项目负责人;
上海市应急科研专项“RADAR”-等温扩增偶联的病毒核酸检测新技术及便携式配套仪器研发新型冠状病毒肺炎（COVID-19）（2020XGZX022），2020.01-2020.12, 50万元, 项目负责人；
论文下载
支撑材料