Huang Kai

Selected Publications

  • •  

    Ren H, Hu W, Jiang T, Yao Q, Qi Y, Huang K. Mechanical stress induced mitochondrial dysfunction in cardiovascular diseases: Novel mechanisms and therapeutic targets. Biomedicine & Pharmacotherapy. 2024; 174, 116545. (通讯作者). JCR Q1

    •  

    Nobel Chengong Zong , Kai Huang , Xia Yang , Hua Linda Cai. Expand the Success of Screening to Reduce Aortic Aneurysm Mortality - Progress Interpretation and New Fronts. Trends in Cardiovascular Medicine. 2024.  (共一).  JCR Q1

    •  

    Huang K*, Wu Y*, Zhang Y, Youn JY, Cai H. Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication. Redox Biology. 2022; 58:102521. 中科院一区TOP

    •  

    Huang K*, Narumi T*, Zhang Y, Li Q, Murugesan P, Wu Y, Liu NMJ, Cai H. Targeting miR-192-5p, a downstream effector of NOXs, reverses endothelial dihydrofolate reductase deficiency to attenuate abdominal aortic aneurysm formation. Hypertension. 2021;78(2):282-293. 中科院一区TOP

    •  

    Huang K*, Zhang P*, Zhang Z*, Youn JY*, Wang C, Zhang H, Cai H. Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and viral infections: Efficacies and mechanisms. Pharmacology & Therapeutics. 2021;225:107843. ESI Highly Cited Paper 中科院一区TOP

  • •  

    Huang K*, Wang Y*, Siu KL*, Zhang Y, Cai H. Targeting feed-forward signaling of TGFβ/NOX4/DHFR/eNOS uncoupling/TGFβ axis with anti-TGFβ and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics. Redox Biology. 2021;38:101757. 中科院一区TOP

    •  

    Huang K, Bao H, Yan ZQ, Wang L, Zhang P, Yao QP, Shi Q, Chen XH, Wang KX, Shen BR, Qi YX, Jiang ZL. MicroRNA-33 protects against neointimal hyperplasia induced by arterial mechanical stretch in the grafted vein. Cardiovascular Research. 2017, 113(5):488-497. (Cover Article & Editor Choice & Editorial; High impact Cardiovascular Research; Recent Cardiovascular Research highlights from China). 中科院一区TOP

    •  

    Jiang J, Huang K, Xu S, Garcia JGN, Wang C, Cai H. Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction. Redox Biology. 2020 ;36:101638. 中科院一区TOP

    •  

    Zhang Y, Murugesan P, Huang K, Cai H. NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets. Nature Reviews Cardiology. 2020 Mar; 17(3):170-194. ESI Highly Cited Paper 中科院一区TOP

    •  

    Youn JY, Middlekauff HR, Reudiseuli I, Huang K, Cai H. Endothelial damage in young adult e-cigarette users. Redox Biology. 58 (2023) 102688. 中科院一区TOP