Chuan Xu

  • Tel: +86-021
  • Email: chuanx@sjtu.edu.cn (长期招收实验或生信方向博士后,2023年招分子/细胞生物学实验方向普博生)
  • PI, Bio-X institutes at SJTU. My research involves Bioinformatics, Fungal Pathogens, Comparative/Evolutionary Genomics and Systems Biology. Researches are published in Cell Syst., Cell Rep., PLoS Biol., Mol. Biol. Evol., Nat. Rev. Genet., etc. International students are welcome to apply for my lab's Ph.D. programs.

Education and Research Experience

  • PI, Bio-X institutes at SJTU, Shanghai, China.
  • Postdoctoral Researcher at UMich, USA.
  • Ph.D. at Zhejiang Unviersity, China.

Research Interests

Genome-wide mechanism of eukaryotic transcription and translation and its si...

Genome-wide mechanism of eukaryotic transcription and translation and its significance in species evolution.

Virulence evolution of pathogenic fungi

Virulence evolution of pathogenic fungi

Human disease

Human disease
 

Selected Publications

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    Zhang, J., and Xu, C.  (2022) Gene product diversity: adaptive or not? Trends in Genetics, In press

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    Xu, C., and Zhang, J (2021) Mammalian circular RNAs result largely from splicing errors. Cell Reports., 36:109439.

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    Xu, C., and Zhang, J. (2020). Mammalian alternative translation initiation is mostly nonadaptive. Molecular Biology and Evolution. Mar 7. pii: msaa063. doi: 10.1093/molbev/msaa063.

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    Xu, C., and Zhang, J. (2020) A different perspective on alternative cleavage and polyadenylation. Nature Review Genetics., doi: 10.1038/s41576-019-0198-z

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    Xu, C., Park, J. K., and Zhang, J. (2019). Evidence that alternative transcriptional initiation is largely nonadaptive. PLoS biology, 17(3), e3000197.

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    Xu, C., and Zhang, J. (2018). Alternative Polyadenylation of Mammalian Transcripts Is Generally Deleterious, Not Adaptive. Cell systems. 6 (6), 734-742.e4