Bo Cao

  • Tel: +86-021
  • Email: caobosjtu@sjtu.edu.cn
  • Address:

Selected Publications

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    Hu J, Yim D, Ma D, Huber MS, Davis N, Bacusmo JM, Vermeulen S, Zhou J, Begley TJ, DeMott MS,   Levine SS, Crécy-Lagard V, Dedon PC*, Cao B*. Quantitative mapping of the cellular small RNA landscape with AQRNA-seq. Nat. Biotech. 2021 Aug;39(8):978-988.

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    Kaiser S, Byrne SR, Ammann G, Asadi Atoi P, Borland K, Brecheisen R, DeMott MS, Gehrke T, Hagelskamp F, Heiss M, Yoluc Y, Liu L, Zhang Q, Dedon PC, Cao B*, Kellner S*. Strategies to avoid artifacts in mass spectrometry-based epitranscriptome analyses. Angew Chem Int Ed Engl. 2021 Oct 25;60(44):23885-23893.

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    Cao B*#, Wu X#,  Zhou J, Wu H, Liu L, Zhang Q, DeMott MS, Gu C, Wang L, You D*, Dedon PC*, Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage, Nucleic Acids Res, 2020, 48(12), 6715–6725

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    Wu X#, Cao B#, Aquino P, Chiu TP, Chen C, Jiang S, Deng Z, Chen S, Rohs   R, Wang L, Galagan JE, Dedon PC*. Epigenetic competition reveals   density-dependent regulation and target site plasticity of phosphorothioate   epigenetics in bacteria. Proc Natl Acad Sci USA. 2020. Jun 23;117(25):14322-14330. 

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    Cao B #, Chen C#, DeMott MS, Cheng Q, Clark TA, Xiong X, Zheng X, Butty V, Levine SS, Yuan G, Boitano M, Luong K, Song Y, Zhou X, Deng Z, Turner SW, Korlach J, You D, Wang L, Chen S, Dedon PC. Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences. Nat Commun. 2014, 5, 3951.

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    Cao B, Cheng Q, Gu C, Yao F, DeMott MS, Zheng X, Deng Z, Dedon PC, You D*. Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate-based restriction system in Salmonella. Mol Microbiol. 2014, 93 (4), 776-85.

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    Cheng Q#, Cao B#, Yao F, Li J, Deng Z, You D*. Regulation of DNA phosphorothioate modifications by the transcriptional regulator DptB in Salmonella. Mol Microbiol. 2015, 97 (6), 1186

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    Cao B, Zheng X, Cheng Q, Yao F, Zheng T, Ramesh Babu I, Zhou H, Dedon PC, You D*. In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex. Sci Rep. 2015, 5, 12513.

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    Cao B, Yao F, Zheng X, Cui D, Shao Y, Zhu C, Deng Z, You D*. Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment. Chembiochem. 2012, 13 (15), 2234-42.

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    Kellner SM, DeMott MS, Cheng C, Russell B, Cao B, Dedon PC*. Oxidation of labile phosphorothioate DNA modifications leads to lethal genomic instability. Nat Chem Biol. 2017 Aug;13(8),888-894.