Professor
In order to increase the yields and titers, synthetic biology have been widely applied to increase microbial tolerance to bioproducts, However, synthetic biology microorganisms (SynBioMs) can enter natural water environment through wastewater discharge. The molecular modification methods to enhance microbial tolerance to bioproducts are likely to enhance microbial resistance to disinfectants and help microorganisms pass through the water treatment processes, which will seriously threaten the biosafety of drinking water.
Xiaohui Bai，Xinghua Zhi，Huifeng Zhu，Mingqun Meng，Mingde Zhang. Real-time ArcGIS and heterotrophic plate count based chloramine disinfectant control in water distribution system. Water Research, 2015, 68（1）:812-820.
Xiaohui Bai, Xiaolin Ma, Fengming Xu, Jing Li, Hang Zhang, Xiang Xiao. The drinking water treatment process as a potential source of affecting the bacterial antibiotic resistance. Science of the Total Environment, 2015,533:24-31
Hira Khan, Xiaocao Miao, Mingkun Liu, Shakeel Ahmad, Xiaohui Bai*. Behavior of last resort antibiotic resistance genes (mcr-1 and blaNDM-1) in a drinking water supply system and their possible acquisition by the mouse gut flora. Environmental Pollution, 2020, 259: https://doi.org/10.1016/j.envpol.2019.113818
Huang xuejing, Tan Zaigao, Wei Jiayu, Bai Xiaohui. Super-rubust synthetic microorganism can get chlorine resistance in advance and transfer their inserted DNA sequence in genome to indigenous bacteria in water. Water Research, 2025, 281:123594
Xiaocao Miao, Lingling Zhu, Xiaohui Bai, Bacterial community assembly and beta-lactamase (bla) genes regulation in a full-scale chloraminated drinking water supply system. Journal of Environmental Chemical Engineering. 2022，10（3）：107677.
Zengyi Hu, Xiaohui Bai. Self-repair and resuscitation of viable injured bacteria in chlorinated drinking water: Achromobacter as an example. Water Research, 2023, 245:120585
Miao, X., Liu, C., Liu, M., Han, X., Zhu, L., Bai, X., Occurrence and dissemination of viral pathogens and virulence factor genes in a full-scale drinking water supply system. Journal of Hazardous Materials. 2022,432:128694.
Xiaocao Miao, Xiaohui Bai. Characterization of the synergistic relationships between nitrification and microbial regrowth in the chloraminated drinking water supply system. Environmental Research, 2021, 199:111252
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