Professor
In order to increase the yields and titers, synthetic biology have been widely applied to increase microbial tolerance to bioproducts, However, synthetic biology microorganisms (SynBioMs) can enter natural water environment through wastewater discharge. The molecular modification methods to enhance microbial tolerance to bioproducts are likely to enhance microbial resistance to disinfectants and help microorganisms pass through the water treatment processes, which will seriously threaten the biosafety of drinking water.
Tanghao Liu, Tao Dong, Ting Zhang, Xiaohui Bai*. Mg2+ in drinking water boosts Salmonella infection risk by rewiring gut ecology and virulence. Nature Water, 2026, 4:307-319. https://doi.org/10.1038/s44221-026-00584-2
Tanghao Liu, JianingXiu, XuejingHuang, BinGeng, LingHu, XiaohuiBai*. Material-driven microbiologically influenced corrosion mechanisms in drinking water distribution systems. Water Research, 2026, 288:124729
Xuejing Huang, Jianing Xiu, Tanghao Liu, Yongquan Chen, Meifeng Tao, Xiaohui Bai*. Antibiotic factories on the move: Synthetic bacteria survive drinking water treatment and continuously produce antibiotics. Water Research, 2026, 305, 126462
Huang xuejing, Tan Zaigao, Wei Jiayu, Bai Xiaohui. Super-rubust synthetic microorganism can get chlorine resistance in advance and transfer their inserted DNA sequence in genome to indigenous bacteria in water. Water Research, 2025, 281:123594
Xuejing Huang , Tanghao Liu , Jianing Xiu , Xiaohui Bai *. Pre-chlorination in source water endows ARB with resistance to chlorine disinfection in drinking water treatment. Journal of Hazardous Materials. 2025,494:138670. https://doi.org/10.1016/j.jhazmat.2025.138670
Xiaohui Bai，Xinghua Zhi，Huifeng Zhu，Mingqun Meng，Mingde Zhang. Real-time ArcGIS and heterotrophic plate count based chloramine disinfectant control in water distribution system. Water Research, 2015, 68（1）:812-820.
Miao, X., Liu, C., Liu, M., Han, X., Zhu, L., Bai, X., Occurrence and dissemination of viral pathogens and virulence factor genes in a full-scale drinking water supply system. Journal of Hazardous Materials. 2022,432:128694.
Hira Khan, Mingkun Liu, Masood ur Rehman Kayani, Shakeel Ahmad, Jingdan Liang, Xiaohui Bai. DNA phosphorothioate modification facilitates the dissemination of mcr-1 and blaNDM-1 in drinking water supply systems. Environmental Pollution, 2021,268:115799
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