Yi Xiao

Special Researcher/Tenure-track Associate Professor

  • Tel: +86-021-34208601
  • Email: yi_xiao@sjtu.edu.cn
  • Address: Xitong Building (Room C404), 800 Dongchuan RD. Minhang District, Shanghai, China

Education and Research Experience

  • 2017-Current, Professor, Shanghai Jiao Tong University
  • 2010-2016, Research Scientist and Postdoc,Washington University in St. Louis, USA
  • 2008-2010, Postdoc, South China Sea Institute of Oceanology, Chinese Academy of Sciences, China
  • 2019-Current, the Editorial Board of Applied and Environmental Microbiology

Selected Publications

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    Jiawei Li, Ziqing Qin, Baohui Zhang, Xiaofeng Wu, Jing Wu, Lifeng Peng, Yi Xiao*. Development of transcriptional factor-based whole-cell biosensors to monitor and degrade antibiotics using mutant cells obtained via adaptive laboratory evolution. Journal of Hazardous Materials. 2024, 473, 134536

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    Mingtao Zhao, Xulin Hong, Abdullah, Rulin Yao, Yi Xiao*. Rapid biosynthesis of phenolic glycosides and their derivatives from biomass-derived hydroxycinnamates. Green Chemistry, 23, 838-847

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    Abdullah, Pujie Wang, Tongren Han, Wei Liu, Wenting Ren, Yuehong Wu, and Yi Xiao*. Adenine base editing system for Pseudomonas and prediction workflow for protein dysfunction via ABE. ACS Synthetic Biology. 11(4):1650-1657.

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    Mingtao Zhao, Yankai Tao, Xiaofeng Wu, Yi Xiao*. One-pot efficient biosynthesis of 4-hydroxyphenylacetic acid and its analogues from lignin-related p-coumaric and ferulic acids. ACS Sustainable Chemistry & Engineering. 9(18):6400-6409

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    Mingtao Zhao, Ziqing Qin, Abdullah, and Yi Xiao*. Construction of biocatalytic cascades for the synthesis of benzylisoquinoline alkaloids from p-coumaric acid derivatives and dopamine. Green Chemistry, 24, 3225 - 3234

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    Shun Zhang, Xiaofeng Wu, and Yi Xiao*. Conversion of lignin-derived 3-methoxycatechol to the natural product purpurogallin using bacterial P450 GcoAB and laccase CueO. Applied Microbiology and Biotechnology . 106(2):593-603. 

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    Mingtao Zhao, Xiaofeng Wu, Yankai Tao and Yi Xiao*. Full use of lignocellulosic biomass for efficient

    synthesis of L-tyrosine and its analogues by engineering microbial consortia. Green Chemistry. 2024, 26, 6760-6773

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    Zhengzheng Jiang, Abdullah, Shun Zhang, Yuli Jiang, Rui Liu, and Yi Xiao*. Development and optimization of CRISPR prime editing system in photoautotrophic cells. Molecules. 27(6):1758.

     

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    Ruilian Yao, Di Liu, Xiao Jia, Yuan Zheng, Wei Liu, Yi Xiao. CRISPR-Cas9/Cas12a biotechnology and application in bacteria. Synthetic and Systems Biotechnology. 3(3):135-149

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    Yi Xiao, Christopher H. Bowen, Di Liu, Fuzhong Zhang.  Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis. Nature Chemical Biology 12, 339–344

Teaching Experiences

  • Fundamentals of natural science
  • CRISPR gene editing
  • English writing 
  • National 1000 Youth Talents Program 2018
  • National Key R&D Program of China 2019/2020
  • National Natural Science Foundation of China 2019
  • Science and Technology Commission of Shanghai Municipality 2018

Selected Grants

Students