Yawen He

  • Tel: +86-13564385795
  • Email: yawenhe@sjtu.edu.cn
  • Address: Dongchuan Road #800, Biology and Pharmacy Building 4D-303
  • Ya-Wen He received his BSc in Biology from Central China Normal University in 1992. He obtained his Ph.D. from National University of Singapore in 2006. He then worked as a research fellow at the Institute of Molecular and Cell Biology. In 2010, he joined Shanghai Jiaotong University as a principal investigator.

Selected Publications

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    He Ya-Wen and Zhang Lian-Hui. Quorum sensing and virulence regulation in Xanthomonas campestris. FEMS Microbiology Reviews. 2008, 32: 842–857

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    Zhou L, Zhang LH, Cámara M, He Ya-Wen. The DSF Family of Quorum Sensing Signals: Diversity, Biosynthesis, and Turnover in Xanthomonas. Trends in Microbiology. 2017, 25(4):293-303.

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    Song K, Chen B, Cui Y, Zhou L, Chan KG, Zhang HY, He Ya-Wen. The Plant Defense Signal Salicylic Acid Activates the RpfB-Dependent Quorum Sensing Signal Turnover via Altering the Culture and Cytoplasmic pH in the Phytopathogen Xanthomonas campestris. mBio. 2022,13(2): e0364421. 

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    Chen B, Li RF, Zhou L, Song K, Poplawsky AR, He Ya-Wen. The phytopathogen Xanthomonas campestris scavenges hydroxycinnamic acids in planta via the hca cluster to increase virulence on its host plant. Phytopathology Research, 2022, 4: 12.

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    Chen B, Li RF, Zhou L, Qiu JH, Song K, Tang JL, He Ya-Wen. The phytopathogen Xanthomonas campestris utilizes the divergently transcribed pobA/pobR locus for 4-hydroxybenzoic acid recognition and degradation to promote virulence. Molecular Microbiology. 2020, 114(5): 870-886.

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    Diab AA, Cao XQ, Chen H, Song K, Zhou L, Chen B, He Ya-Wen. BDSF Is the Predominant In-Planta Quorum-Sensing Signal Used During Xanthomonas campestris Infection and Pathogenesis in Chinese Cabbage. Mol Plant Microbe Interact. 2019, 32(2):240-254.

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    Cao, XQ, Zhou L, Chen B, He Ya-Wen. Biosynthesis of Xanthomonas yellow pigment xanthomonadins involves an ATP-dependent 3- HBA:ACP ligase and an unusual type II polyketide synthesis pathway. Molecular Microbiology. 2018, Oct; 110(1):16-32.

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    Sun S, Chen B, Jin ZJ, Zhou L, Fang YL, Thawai C, Rampioni G, He Ya-Wen. Characterization of the multiple molecular mechanisms underlying RsaL control of phenazine-1-carboxylic acid biosynthesis in the rhizosphere bacteriumPseudomonas aeruginosa PA1201. Molecular Microbiology. 2017, 104(6):931-947.

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    Zhou Lian*, Wang Xing-Yu*, Sun Shuang, Yang Li-Chao, Jiang Bo-Le, He Ya-Wen. Identification and Characterization of Naturally Occurring DSF-Family Quorum Sensing Signal Turnover System in the Phytopathogen Xanthomonas. Environmental Microbiology, 2015, 17(11):4646–4658.

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    Jin Kaiming*, Zhou Lian*, Jiang Haixia, Sun Shuang, Fang Yunling, Liu Jianhua, Zhang Xuehong, He Ya-Wen. Engineering the central biosynthetic and secondary metabolic pathways of Pseudomonas aeruginosa strain PA1201 to improve phenazine-1-carboxylic acid production. Metabolic Engineering, 2015, 32:30-38.