Qian Liu

Research Professor

  • Tel:
  • Email: liuqian1018@sjtu.edu.cn
  • Address:

Selected Publications

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    Mesophilic Argonaute-based isothermal detection of SARS-CoV-2, Frontiers in Microbiology, 2022.

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    Argonaute-integrated isothermal amplification for rapid, portable, multiplex detection of SARS-CoV-2 and influenza viruses. Biosensors and Bioelectronics. 2022.

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    Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity, Nucleic Acids Research, 2022.

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    Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations. Nucleic Acids Research, 2021.

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    Utility of B‑Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability, ACS Chemical Reviews, 2018

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    The state-of-the-art strategies of protein engineering for enzyme stabilization, Biotechnology Advances, 2018

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    Argonaute with stepwise endonuclease activity promotes specific and multiplex nucleic acid detection. Bioresources and Bioprocessing. 2021.

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    Probing and Engineering the Fatty Acyl Substrate Selectivity of Starter Condensation Domains of Nonribosomal Peptide Synthetases in Lipopeptide Biosynthesis, Biotechnology Journal, 2019(Front cover)

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     A hyperthermophilic Argonaute from Ferroglobus placidus with specificity on guide binding pattern. Frontiers in Microbiology, 2021.

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    Characterization of protein interaction surface on fatty acyl selectivity of starter condensation domain in lipopeptide biosynthesis, Applied Microbiology and Biotechnology, 2019