Xiankun Wang, Yuchun Zhao, Yaojie Gao, Xiangkun Luo, Aiqing Du, Zixin Deng, Zabriskie TM, Xinyi He*, Ming Jiang*. A [3Fe-4S] cluster and tRNA-dependent aminoacyltransferase BlsK in the biosynthesis of Blasticidin S. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2102318118. doi: 10.1073/pnas.2102318118.
Hao Yu, Jiayi Li, Guang Liu, Gong Zhao, Yuli Wang, Wenyue Hu, Zixin Deng, Geng Wu, Jianhua Gan, Yi-Lei Zhao*, Xinyi He*. DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses. Nucleic Acids Research 2020 Sep 4;48(15):8755-8766. doi: 10.1093/nar/gkaa574.
Hongliang Qian, Hao Yu, Peifei Li, E Zhu, Qingqing Yao, Cui Tai, Zixin Deng, Kenn Gerdes, Xinyi He*, Jianhua Gan*, Hong-Yu Ou*. Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex. Nucleic Acids Research. 2019 Aug 22;47(14):7690-7702.
Guang Liu, Wencheng Fu, Zhengyi Zhang, Yao He, Hao Yu, Yuli Wang, Xiaolei Wang, Yi-Lei Zhao, Zixin Deng, Geng Wu*, Xinyi He*. Structural basis for the recognition of sulfur in phosphorothioated DNA. Nature Communications. 2018 Nov 8;9(1):4689.
Hao Yu, Guang Liu, Gong Zhao, Wenyue Hu, Geng Wu, Zixin Deng, Xinyi He*. Identification of a conserved DNA sulfur recognition domain by characterizing the phosphorothioate-specific endonuclease SprMcrA from Streptomyces pristinaespiralis. Molecular Microbiology. 2018 Nov;110(3):484-497.
Xiankun Wang, Aiqing Du, Guiyang Yu, Zixin Deng, Xinyi He*. Guanidine N-methylation by BlsL Is Dependent on Acylation of Beta-amine Arginine in the Biosynthesis of Blasticidin S. Front Microbiol. 2017 Aug 22;8:1565.
Gong Zhao, Geng Wu, Yan Zhang, Guang Liu, Tiesheng Han, Zixin Deng, and Xinyi He*. Structure of the N-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry. Nucleic Acids Research 2014, 42(12): 8115-8124.
Tiesheng Han, Megumu Yamada-Mabuchi, Gong Zhao, Li Li, Guang Liu, Hong-Yu Ou, Zixin Deng, Yu Zheng*, and Xinyi He*. Recognition and cleavage of 5-methylcytosine DNA by bacterial SRA-HNH proteins. Nucleic Acids Research 2015, 43(2): 1147-1159.