Professor/Tenured Associate Professor
Genome-wide mutagenesis links multiple metabolic pathways with actinorhodin production in Streptomyces coelicolor. Xu Z*, Li Y, Wang Y, Deng Z, Tao M*. Appl Environ Microbiol, March 2019, 85(7). e03005-18. doi: 10.1128/AEM.03005-18.
Engineered Streptomyces lividans strains for optimal identification and expression of cryptic biosynthetic gene clusters. Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z*, Tao M*. Front Microbiol. Dec. 2018, 9:3042. doi: 10.3389/fmicb.2018.03042.
Biosynthesis of tropolones in Streptomyces spp: interweaving biosynthesis and degradation of phenylacetic acid and hydroxylations on tropone ring. Chen X, Xu M, Lü J, …Lin S, Deng Z, Tao M*. Appl Environ Microbiol, 2018, doi: 10.1128/AEM.00349-18.
Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement. Gao G, Liu X, Xu M, … Jiang M,* Lin S.* Tao M*. Cell Chem Biol, 2017, 24:881-891.
Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy. Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M*. Metab Eng, 2016, 38:418-426.
Functional genome mining for metabolites encoded by large gene clusters through heterologous expression of a whole-genome bacterial artificial chromosome library in Streptomyces spp. Xu M, Wang Y, Zhao Z, … Pang X, Deng Z, Tao M*. Appl Environ Microbiol, 2016, 82:5795-5805.
Hybrubins: bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes. Zhao Z, Shi T, Xu M, … Deng Z, Pang X*, Tao M*. Org Lett, 2016, 18:572-575.
A cellulose synthase-like protein involved in hyphal tip growth and morphological differentiation in Streptomyces. Xu H, Chater K F, Deng Z, and Tao M*. Journal of Bacteriology, 2008, 190(14): 4971-4978.
A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA. Li W, Wu J, Tao W, Zhao C, Wang Y, He X, Chandra G, Zhou X, Deng Z, Chater K F, and Tao M*. FEMS Microbiology Letters, 2007, 266(1): 20-28.