赵心清

教授

  • 电话:+86-021-34206673
  • 邮箱:xqzhao@sjtu.edu.cn

学术经历

  • 1993年本科毕业于东北师范大学生物系,获得学士学位;
  • 1996年毕业于东北师范大学遗传与细胞研究所,获得硕士学位;
  • 2006年初毕业于韩国明知大学,获得博士学位;
  • 2007-2009年由德国洪堡基金会的资助,于德国Tuebingen大学药学院进行博士后研究;
  • 1998年3月起工作于大连理工大学生命科学与技术学院,2006年晋升副教授,2008年起任博士生导师,2011年底晋升教授。2014年10月起被聘为上海交通大学教授,就职于生命科学技术学院。

研究方向

微生物功能基因及多样性

微生物多样性及在化妆品、医药及能源生产的应用 

微生物多组学分析揭示抗逆性及高产机理

微生物多组学分析揭示抗逆性及高产机理

微生物代谢工程和合成生物学育种

微生物代谢工程和合成生物学育种

代表论著

  • •  

    Zhang MM, Xiong L, Tang YJ, Mehmood MA, Zhao ZB, Bai FW, Zhao XQ*. 2019. Enhanced acetic acid stress tolerance and ethanol production in Saccharomyces cerevisiae by modulating expression of the de novo purine biosynthesis genes Biotechnology for Biofuels 12: 116.

    •  

    Li JX, Zhang F, Li J, Zhang Z, Bai FW, Chen J, Zhao XQ*. 2019. Rapid production of lignocellulolytic enzymes by Trichoderma harzianum LZ117 isolated from Tibet for biomass degradation. Bioresource Technology 292:122063. doi: 10.1016/j.biortech.2019.122063.

    •  

    Tang RQ, Ye PL, Alper H, Liu ZY, Zhao XQ*, Bai FW. 2019. Identification and characterization of novel xylose isomerases from a Bos taurus fecal metagenome. Applied Microbiology and Biotechnology 103(23-24):9465-9477.

    •  

    Cheng C, Tang RQ, Xiong L, Hector RE, Bai FW, Zhao XQ*. 2018. Association of improved oxidative stress tolerance and alleviation of glucose repression with superior xylose utilization capability by a natural isolate of Saccharomyces cerevisiae. Biotechnology for Biofuels, 11:28.  

     

    •  

    Zhang F, Zhao XQ*, Bai FW. 2018. Improvement of cellulase production in Trichoderma reesei Rut-C30 by overexpression of a novel regulatory gene Trvib-1. Bioresource Technology 247: 676-683.

  • •  

    Zhang MM, Zhang KY, Memhood MA, Zhao ZBK, Bai FW, Zhao XQ*. 2017. Deletion of acetate transporter gene ADY2 improved tolerance of Saccharomyces cerevisiae against multiple stresses and enhanced ethanol production in the presence of acetic acid. Bioresource Technology 245(Pt B):1461-1468. 

    •  

    Khatun MM, Yu XS, Kondo A, Bai FW, Zhao XQ*. 2017. Improved ethanol production at high temperature by consolidated bioprocessing using Saccharomyces cerevisiae strain engineered with artificial zinc finger protein. Bioresource Technology 245(Pt B):1447-1454. 

    •  

    Li YH, Zhang XY, Xiong L, M. Mehmood A, Zhao XQ*, Bai FW. 2017. On-site cellulase production and efficient saccharification of corn stover employing cbh2 overexpressing Trichoderma reesei with novel induction system. Bioresource Technology 238:643-649.

    •  

    Zhang XY, Li YH, Zhao XQ*, Bai FW. 2017. Constitutive cellulase production from glucose using the recombinant Trichoderma reesei strain overexpressing an artificial transcription activator. Bioresource Technology 223:317-322.

    •  

    Zhang F, Bai FW, Zhao XQ*. 2016. Enhanced cellulase production from Trichoderma reesei Rut-C30 by engineering with an artificial zinc finger protein library. Biotechnology Journal 11(10):1282-1290.

教学情况

  • 本科生课程:《食品与工业微生物学》、《代谢工程》、《分子生物学》、《生物学科前沿介绍》等;
  • 研究生课程:《工业微生物学》、《微生物生理与代谢调控》、《生物制造》等。