赵心清

教授

  • 电话:+86-021-34206673
  • 邮箱:xqzhao@sjtu.edu.cn

学术经历

  • 1993年本科毕业于东北师范大学生物系,获得学士学位;
  • 1996年毕业于东北师范大学遗传与细胞研究所,获得硕士学位;
  • 2006年初毕业于韩国明知大学,获得博士学位;
  • 2007-2009年由德国洪堡基金会的资助,于德国Tuebingen大学药学院进行博士后研究;
  • 1998年3月起工作于大连理工大学生命科学与技术学院,2006年晋升副教授,2008年起任博士生导师,2011年底晋升教授。2014年10月起被聘为上海交通大学教授,就职于生命科学技术学院。

研究方向

微生物功能基因及多样性

微生物多样性及在化妆品、医药及能源生产的应用 

微生物多组学分析揭示抗逆性及高产机理

微生物多组学分析揭示抗逆性及高产机理

微生物代谢工程和合成生物学育种

微生物代谢工程和合成生物学育种

代表论著

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    Zhang F, Zhao XQ*, Bai FW. 2018. Improvement of cellulase production in Trichoderma reesei Rut-C30 by overexpression of a novel regulatory gene Trvib-1. Bioresource Technology 247: 676-683.

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    Zhang MM, Zhang KY, Memhood MA, Zhao ZBK, Bai FW, Zhao XQ*. 2017. Deletion of acetate transporter gene ADY2 improved tolerance of Saccharomyces cerevisiae against multiple stresses and enhanced ethanol production in the presence of acetic acid. Bioresource Technology 245(Pt B):1461-1468. 

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    Li YH, Zhang XY, Xiong L, M. Mehmood A, Zhao XQ*, Bai FW. 2017. On-site cellulase production and efficient saccharification of corn stover employing cbh2 overexpressing Trichoderma reesei with novel induction system. Bioresource Technology 238:643-649.

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    Siamphana C, Jantima Arnthong J, Tharad S, Zhang F, Yang J, Laothanachareon T, Chuetor S, Champreda V, Zhao XQ*, Suwannarangsee S*. 2021. Production of D-galacturonic acid   from pomelo peel using the crude enzyme from recombinant   Trichoderma reesei   expressing a heterologous exopolygalacturonase gene. Journal of Cleaner Production 331, 129958.

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    Ye PL, Wang XQ, Yuan B, Liu CG, Zhao XQ*. 2022. Manipulating cell flocculation-associated protein kinases in Saccharomyces cerevisiae enables improved stress tolerance and efficient cellulosic ethanol production. Bioresource Technology 348:126758.

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    Li J, Zeng Y, Wang WB, Wan QQ, Liu CG, R den Haan R, van Zyl WH. Zhao XQ*. 2022. Increasing extracellular cellulase activity of the recombinant Saccharomyces cerevisiae by engineering cell wall related proteins for improved consolidated processing. Bioresource Technology 365:128132.

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    Ye PL, Yuan B, Wang XQ, Zhang MM, Zhao XQ*. 2023. Modification of phosphorylation sites in the yeast lysine methyltransferase Set5 exerts influences on the mitogen-activated protein kinase Hog1 under prolonged acetic acid stress. Microbiology Spectrum 11(2): e0301122.

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    Fan SM, Li ZQ, Zhang SZ, Chen LY, Wei XY, Liang J, Zhao XQ*, Su C*. 2023. Multi-integrated approach for unravelling small open reading frames potentially associated with secondary metabolism in Streptomyces. mSystems. e0024523.

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    Yang J, Yue HR, Pan LY, Feng JX, Zhao S, Suwannarangsee S, Chempreda V, Liu CG, Zhao XQ*. 2023. Fungal strain improvement for efficient cellulase production and lignocellulosic biorefinery: current status and future prospects. Bioresource Technology 385:129449.

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    Zhang FL, Zhang L, Zeng DW, Liao S, Fan YC, Champreda V, Runguphan W, Zhao XQ*. 2023. Engineering yeast cell factories to produce biodegradable plastics and their monomers: current status and prospects. Biotechnology Advances. 68:108222.

教学情况

  • 本科生课程:《食品与工业微生物学》、《代谢工程》、《分子生物学》、《生物学科前沿介绍》等;
  • 研究生课程:《工业微生物学》、《微生物生理与代谢调控》、《生物制造》等。

学生培养

  • 在读学生
  • 毕业学生