Huang Zhe

Tenure-track Associate Professor

  • Tel: +86-21-34208469
  • Email: zhehuang@sjtu.edu.cn
  • Address:
  • Our research focus is immunometabolic regulation and metabolic diseases. In-vivo, ex-vivo, in-vitro experiments and multiomics-based approaches with various disease models are applied to explore immunometabolic functions of novel hormones and GPCRs and the underlying mechanisms. National & International students are welcomed.

Selected Publications

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    W. Duan, R. Shi, F. Yang, Z. Zhou, L. Wang, Z. Huang*, S. Zang*. (2023) FSTL3 partially mediates the asscoation of increased nonalcoholic fatty liver disease fibrosis risk with acute myocardial infarction in patients with type 2 diabetes mellitus. Cardiovascular Diabetology. 22: 297.(*co-coresponding author)

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    L. Xu*, Z. Huang*, T. H. Lo, J. T. H. Lee, R. Yang, X. Yan, D. Ye, A. Xu and C. M. Wong. (2022) Hepatic PRMT1 ameliorates diet-inuced hepatic steatosis via induction of PGC1a. Theranostics. 12(6): 2502-2518. (*co-first author)

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    R. Zhang, J. Chen, Y. Xiong, L. Wang, X. Huang, T. Sun, B. Zha, Y. Wu, C. Yan, S. Zang, Q. Zhou*, Z. Huang*, J. Liu*. (2022) Increased neutraphil count is associated with the development of chronic kidney disease in patients with diabets. Journal of Diabetes. 14: 442-454.(*co-coresponding author)

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    Z. Huang and A. Xu. (2021) Adipose extracellular vesicles in intercellular and inter-organ crosstalk in metabolic health and diseases. Frontiers in Immunology. 12: 463.

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    Z. Huang, L. Zhong, T. Z. Lee, J. Zhang, D. Wu, L. Geng, Y. Wang, C. Wong and A. Xu. (2017) The FGF21-CCL11 axis mediates beiging of white adipose tissues by coupling sympathetic nervous system to type 2 immunity. Cell Metabolism. 26(3): 493-508.

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    L. Geng, B. Liao, L. Jin, Z. Huang, C. R. Triggle, H. Ding, J. Zhang, Y. Huang, Z. Lin and A. Xu. (2019) Exercise alleviates obesity-induced metabolic dysfunction via enhancing FGF21 sensitivity in adipose tissues. Cell Reports. 26(10): 2738-2752.

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    Z. Huang, A. Xu, B. M. Y. Cheung. (2017) The potential role of fibroblast growth factor 21 in lipid metabolism and hypertension. Current Hypertension Reports. 19(4): 28-33.

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    T. Z. Lee*, Z. Huang*, K. Pan, J. Zhang, C. W. Woo, C. Wong and A. Xu. (2016) Adipose-derived LCN14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice. Diabetologia. 59(3): 604-613. (*co-first author)

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    C. M. Wong, Y. Wang, T. H. Lee, Z. Huang, D. Wu, A. Xu and S. L. Lam. (2014) Adropin is a brain membrane-bound protein regulating physical activity via the NB-3/Notch signaling pathway in mice. The Journal of Biological Chemistry 289: 25976-25986.

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    K. Y. Kong, H. M. Tang, K. Pan, Z. Huang, T. Z. Lee, A. G. Hinnebusch, D. Y. Jin and C. M. Wong. (2014) Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing. Nucleic Acids Res 42(1): 643-660.