Xiaoxia Xia

Professor/Tenured Associate Professor

  • Tel: +86-021-34207254
  • Email: xiaoxiaxia@sjtu.edu.cn
  • Address:
  • Dr. Xia received her PhD in Chemical and Biomolecular Engineering from KAIST. Her current research focuses on developing synthetic biology tools and creating microbial hosts for the design and sustainable production of advanced protein-based functional materials.

Selected Publications

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    Chen MT†, Hu CF†, Huang HB, Qian ZG*, Xia XX*. Spatially directed biosynthesis of quantum dots via spidroin templating in Escherichia coli. Angew. Chem. Int. Ed., 2022, 61: e202214177.

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    Qian ZG, Huang SC, Xia XX*. Synthetic protein condensates for cellular and metabolic engineering. Nat. Chem. Biol., 2022, 18: 1330-1340.

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    Wei SP†, Qian ZG†, Hu CF†, Pan F, Chen MT, Lee SY, Xia XX*. Formation and functionalization of membraneless compartments in Escherichia coli. Nat Chem Biol, 2020, 16(10):1143-1148. 

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    Jin Q†, Pan F†, Hu CF, Lee SY, Xia XX*, Qian ZG*. Secretory production of spider silk proteins in metabolically engineered Corynebacterium glutamicum for spinning into tough fibers. Metab Eng, 2022, 70: 102-114.

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    Qin N, Qian ZG, Zhou C, Xia XX*, Tao TH*. 3D electron-beam writing at sub-15 nm resolution using spider silk as a resist. Nat Commun 2021, 12: 5133.

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    Song WW†, Qian ZG†, Liu H, Chen HF, Kaplan DL, Xia XX*. On-demand regulation of dual thermosensitive protein hydrogels. ACS Macro Lett 2021, 10(4):395-400.

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    Qian ZG, Pan F, Xia XX*. Synthetic biology for protein-based materials. Curr Opin Biotechnol, 2020, 65:197-204.

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    Tian KK, Qian ZG, Xia XX*. Synthetic biology-guided design and biosynthesis of protein polymers for delivery. Adv. Drug Deliv. Rev., 2023, 194: 114728.

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    Jiang J†, Zhang S†, Qian Z, Qin N, Song W, Sun L, Zhou Z, Shi Z, Chen L, Li X, Mao Y, Kaplan DL, Gilbert Corder SN, Chen X, Liu M, Omenetto FG, Xia XX*, Tao TH*. Protein bricks: 2D and 3D bio-nanostructures with shape and function on demand. Adv Mater, 2018, 1705919. (Selected as inside back cover).

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    Huang SC†, Fan RX†, Tian KK, Xia XX*, Qian ZG*. Controllable fibrillization reinforces genetically engineered protein elastomer hydrogels. Biomacromolecules, 2021, 22: 961-970.

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    Xia XX†, Qian ZG†, Ki CS, Park YH, Kaplan DL, Lee SY*. Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. PNAS 2010, 107 (32): 14059-14063.