Yanan Du

  • Tel: +86-021
  • Email: yanan.du@sjtu.edu.cn
  • Address:

Selected Publications

  • •  

    Du, Y.; Thanapipatsiri, A.; Blancas Cortez, J. J.; Salas-Solá, X. E.; Lin, C.-Y.; Boal, A. K.; Krebs, C.; Bollinger, J. M.; Yokoyama, K. Azetidine Amino Acid Biosynthesis by Non-Haem Iron-Dependent Enzymes. Nat. Chem. 2026, 18 (3), 492–501. 

    •  

    Du, Y.; Dong, J.; Draelos, M. M.; Collazo-Perez, L. N.; Majer, S. H.; Boal, A. K.; Yokoyama, K. Unusual O–H Activation-Initiated C–C Bond Cleavage Reaction by a Nonheme Fe Enzyme in Antifungal Nucleoside Biosynthesis. J. Am. Chem. Soc. 2025, 147 (33), 30163–30177. 
     

    •  

    Du, Y.#; Qiu, Y.#; Meng, X.; Feng, J.; Tao, J.; Liu, W. A Heterotrimeric Dehydrogenase Complex Functions with 2 Distinct YcaO Proteins to Install 5 Azole Heterocycles into 35-Membered Sulfomycin Thiopeptides. J. Am. Chem. Soc. 2020, 142 (18), 8454–8463. 
     

    •  

    Ding, W.; Zhou, M.; Li, H.; Li, M.; Qiu, Y.; Yin, Y.; Pan, L.; Yang, W.; Du, Y.*; Zhang, X.*; Tang, Z.*; Liu, W*. Biocatalytic Fluoroalkylation Using Fluorinated S-Adenosyl-l-Methionine Cofactors. Org. Lett. 2023, 25 (30), 5650–5655. 
     

    •  

    Du, Y.; Thanapipatsiri, A.; Yokoyama, K. Biosynthesis and Genome Mining Potentials of Nucleoside Natural Products. ChemBioChem 2023, 24 (17), e202300342. 
     

  • •  


    Qiu, Y.#; Du, Y.#; Zhang, F.; Liao, R.; Zhou, S.; Peng, C.; Guo, Y.; Liu, W. Thiolation Protein-Based Transfer of Indolyl to a Ribosomally Synthesized Polythiazolyl Peptide Intermediate during the Biosynthesis of the Side-Ring System of Nosiheptide. J. Am. Chem. Soc. 2017, 139 (50), 18186–18189. 
     

    •  

    Qiu, Y.#; Du, Y.#; Wang, S.; Zhou, S.; Guo, Y.; Liu, W. Radical S-Adenosylmethionine Protein NosN Forms the Side Ring System of Nosiheptide by Functionalizing the Polythiazolyl Peptide S-Conjugated Indolic Moiety. Org. Lett. 2019, 21 (5), 1502–1505.