Hongyu Ou

Professor

Selected Publications

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    Li P, Goh YX, Wang M, Ilic B, Tai C, Deng Z, Djordjevic M, Ou HY* (2023) Antibiotic-induced degradation of antitoxin enhances the transcription of acetyltransferase-type toxin-antitoxin operon. Journal of Antimicrobial Chemotherapy, 78(4):1066-1075. 

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    Wang M, Goh YX, Tai C, Wang H, Deng Z, Ou HY* (2022) VRprofile2: detection of antibiotic resistance-associated mobilome in bacterial pathogens. Nucleic Acids Research, 50(W1):W768-W773.

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    Zhang J, Guan J, Wang M, Li G, Djordjevic M, Tai C, Wang H, Deng Z, Chen Z*, Ou HY* (2023) SecReT6 update: a comprehensive resource of bacterial Type VI Secretion Systems. SCIENCE CHINA Life Sciences, 66(3):626-634.

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    Zhang Y#, Zhang Y#, Xiong Y, Wang H, Deng Z, Song J*, Ou HY* (2021) T4SEfinder: a bioinformatics tool for genome-scale prediction of bacterial type IV secreted effectors using pre-trained protein language model. Briefings in Bioinformatics, DOI: 10.1093/bib/bbab420.

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    Xu Y#, Zhang J#, Wang M, Liu M, Liu G, Qu H, Liu J, Deng Z, Sun J*, Ou HY*, Qu J* (2021) Mobilization of the nonconjugative virulence plasmid from hypervirulent Klebsiella pneumoniaeGenome Medicine, 13(1):119.

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    H. Qian#, H. Yu#, P. Li, E Zhu, Q. Yao, C. Tai, Z. Deng, K. Gerdes, X. He*, J. Gan*, H.Y. Ou* (2019) Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex. Nucleic Acids Research, 47(14):7690-7702

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    M. Liu, X. Li, Y. Xie, D. Bi, J. Sun, J. Li, C. Tai, Z. Deng, H.Y. Ou* (2019) ICEberg 2.0: an updated database of bacterial integrative and conjugative elements. Nucleic Acids Research, 47(D1):D660-D665

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    H. Qian, Q. Yao, C. Tai, Z. Deng, J. Gan*, H.Y. Ou*(2018) Identification and characterization of acetyltransferase-type toxin-antitoxin loci in Klebsiella pneumoniaeMolecular Microbiology, 108(4), 336–349. (Cover Story, and Comment in: Molecular Microbiology, 108(4), 331–335)

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    X. Li, Y. Xie, M. Liu, C. Tai, J. Sun, Z. Deng, H.Y. Ou* (2018) oriTfinder: a web-based tool for the identification of origin of transfers in DNA sequences of bacterial mobile genetic elements. Nucleic Acids Research, 46(W1):W229–W234. 

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    Y. Xie#, Y. Wei#, Y. Shen#, X. Li, H. Zhou, C. Tai, Z. Deng, H.Y. Ou* (2018) TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci. Nucleic Acids Research, 46:D749-D753.