Qing Lu

Special Researcher/Tenure-track Associate Professor

Selected Publications

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    Feng M#, Wei X#, Zheng X, Liu L, Lin L, Xia M, He G*, Shi Y*, Lu Q*. Decoding Missense Variants by Incorporating Phase Separation via Machine Learning. Nat Commun. 2024 Sep 27;15(1):8279.

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    Qiu C#, Zhang L#, Yong C, Hu R, Sun Y, Wang B, Fang L, Zhu GJ, Lu Q, Wang J*, Ma X*, Zhang L*, Wan G*. Stub1 promotes degradation of the activated Diaph3: A negative feedback regulatory mechanism of the actin nucleator. J Biol Chem. 2024 Oct;300(10):107813.

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    Dai Y, Idorn M, Serrero MC, Pan X, Thomsen EA, Narita R, Maimaitili M, Qian X, Iversen MB, Reinert LS, Flygaard RK, Chen M, Ding X, Zhang BC, Carter-Timofte ME, Lu Q, Jiang Z, Zhong Y, Zhang S, Da L, Zhu J, Denham M, Nissen P, Mogensen TH, Mikkelsen JG, Zhang SY, Casanova JL, Cai Y*, Paludan SR*. TMEFF1 is a neuron-specific restriction factor for herpes simplex virus. Nature. 2024 Aug;632(8024):383-389.

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    Ruan K, Bai G, Fang Y, Li D, Li T, Liu X, Lu B, Lu Q, Songyang Z, Sun S, Wang Z, Zhang X, Zhou W, Zhang H. Biomolecular condensates and disease pathogenesis. Sci China Life Sci. 2024 Sep;67(9):1792-1832.

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    Cao Y#, Tian GG#, Hong X, Lu Q, Wei T*, Chen HF*, Wu J*. Reproductive chemical database: a curated database of chemicals that modulate protein targets regulating important reproductive biological processes. Cell Biosci. 2024 Jun 6;14(1):73.

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    Mao Y*, Harvey WT, Porubsky D, Munson KM, Hoekzema K, Lewis AP, Audano PA, Rozanski A, Yang X, Zhang S, Yoo D, Gordon DS, Fair T, Wei X, Logsdon GA, Haukness M, Dishuck PC, Jeong H, Del Rosario R, Bauer VL, Fattor WT, Wilkerson GK, Mao Y, Shi Y, Sun Q, Lu Q, Paten B, Bakken TE, Pollen AA, Feng G, Sawyer SL, Warren WC, Carbone L, Eichler EE*. Structurally divergent and recurrently mutated regions of primate genomes. Cell. 2024 Mar 14;187(6):1547-1562.e13.

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    Li N#, Liu S#, Zhao D#, Du H, Xi Y, Wei X, Liu Q, Müller U, Lu Q*, Xiong W*, Xu Z*. Disruption of Cdh23 exon 68 splicing leads to progressive hearing loss in mice by affecting tip-link stability. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2309656121.

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    Song X#, Hu R#, Chen Y#, Xiao M, Zhang H, Wu S*, Lu Q*. The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development. J Mol Cell Biol. 2024 Jul 1;16(1):mjad083.

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    Yang X#, Wang X#, Zou Y, Zhang S, Xia M, Fu L, Vollger MR, Chen NC, Taylor DJ, Harvey WT, Logsdon GA, Meng D, Shi J, McCoy RC, Schatz MC, Li W, Eichler EE, Lu Q, Mao Y. Characterization of large-scale genomic differences in the first complete human genome. Genome Biol. 2023 Jul 4;24(1):157.

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    Wang H#, Du H#, Ren R, Du T, Lin L, Feng Z, Zhao D, Wei X, Zhai X, Wang H, Dong T, Sun JP, Wu H, Xu Z*, Lu Q*. Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation. Nat Commun. 2023 Mar 24;14(1):1657.