Hongyu Ou

Professor

Selected Publications

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    H. Qian#, H. Yu#, P. Li, E Zhu, Q. Yao, C. Tai, Z. Deng, K. Gerdes, X. He*, J. Gan*, H.Y. Ou* (2019) Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex. Nucleic Acids Research, 47(14):7690-7702

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    M. Liu, X. Li, Y. Xie, D. Bi, J. Sun, J. Li, C. Tai, Z. Deng, H.Y. Ou* (2019) ICEberg 2.0: an updated database of bacterial integrative and conjugative elements. Nucleic Acids Research, 47(D1):D660-D665

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    X. Li, Y. Xie, M. Liu, C. Tai, J. Sun, Z. Deng, H.Y. Ou* (2018) oriTfinder: a web-based tool for the identification of origin of transfers in DNA sequences of bacterial mobile genetic elements. Nucleic Acids Research, 46(W1):W229–W234. 

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    H. Qian, Q. Yao, C. Tai, Z. Deng, J. Gan*, H.Y. Ou*(2018) Identification and characterization of acetyltransferase-type toxin-antitoxin loci in Klebsiella pneumoniae. Molecular Microbiology, 108(4), 336–349. (Cover Story, and Comment in: Molecular Microbiology, 108(4), 331–335)

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     Y. Xie#, L. Tian#, G. Li#, H. Qu, J. Sun, W. Liang, X. Li, X. Wang, Z. Deng, J. Liu*, H.Y. Ou* (2018) Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable blaDHA-1-carrying plasmid by an ST23 strain. Virulence, 9(1):838-844

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    X. Wang#, Y. Xie#, G. Li, J. Liu, X. Li, L. Tian, J. Sun, H.Y. Ou*, H. Qu* (2018) Whole-Genome-Sequencing characterization of bloodstream infection-causing hypervirulent Klebsiella pneumoniae of capsular serotype K2 and ST374. Virulence, 9:1, 510-521.

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    Y. Xie#, Y. Wei#, Y. Shen#, X. Li, H. Zhou, C. Tai, Z. Deng, H.Y. Ou* (2018) TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci. Nucleic Acids Research, 46:D749-D753.

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    J. Li, C. Tai, Z. Deng, W. Zhong, Y. He, H.Y. Ou* (2018) VRprofile: gene-cluster-detection-based profiling of virulence and antibiotic resistance traits encoded within genome sequences of pathogenic bacteria. Briefings in Bioinformatics, 19(4):566-574.

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    D. Bi, X. Jiang, Z.K. Sheng, D. Ngmenterebo, C. Tai, M. Wang, Z. Deng, K. Rajakumar and H.Y. Ou* (2015) Mapping the resistance-associated mobilome of a carbapenem-resistant Klebsiella pneumoniae strain reveals insights into factors shaping these regions and facilitates generation of a 'resistance-disarmed' model organism. Journal of Antimicrobial Chemotherapy, 70:2770-2774.

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    D. Bi, L. Liu, C. Tai, Z. Deng, K. Rajakumar* and H.Y. Ou* (2013) SecReT4: a web-based bacterial type IV secretion system resource. Nucleic Acids Research, 41, D660-D665.