长聘教轨副教授
细菌聚集所形成的生物膜与临床感染密切相关，然而其单细胞时空轨迹和谱系分化等生成机制尚不清楚。我们通过追踪细菌生物膜中单细胞时空轨迹和谱系演变，揭示驱动生物膜形成和细菌命运分化的多细胞间的集体协作机制。
多细胞结构自发形成的宏观形态在自然界普遍存在，并发挥重要生物功能。我们探索多细胞聚落宏观形态发生的规律，揭示其生物力学、细胞间通讯和基质蛋白的驱动机制。
借助先进光片显微和分子生物标记技术，我们追踪生物膜发育过程中单细胞和跨谱系的基因表达动力学，揭示个体命运分化机制。
Boyang Qin, Chenyi Fei, Andrew A. Bridges, Ameya A. Mashruwala, Howard A. Stone, Ned S. Wingreen, and Bonnie L. Bassler, Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy, Science 369, 71-77 (2020).
Boyang Qin and Bonnie L. Bassler, Quorum-sensing control of matrix protein production drives fractal wrinkling and interfacial localization of Vibrio cholerae pellicles, Nat. Commun. 13, 6063 (2022).
Boyang Qin, Chenyi Fei, Bruce Wang, Howard A. Stone, Ned S. Wingreen, and Bonnie L. Bassler, Hierarchical transitions and fractal wrinkling drive bacterial pellicle morphogenesis, Proc. Natl. Acad. Sci. U.S.A. 118, e2023504118 (2021).
Boyang Qin* and Paulo E. Arratia*, Confinement, chaotic transport, and trapping of active swimmers in time-periodic flows, Sci. Adv. 8, eadd6196 (2022). *: co-corresponding author. † Featured as journal cover.
Boyang Qin, Paul F. Salipante, Steve D. Hudson, and Paulo E. Arratia, Flow resistance and structures in viscoelastic channel flows at low Re, Phys. Rev. Lett. 123, 194501 (2019).
Boyang Qin*, Ranjiangshang Ran, Paul F. Salipante, Steve D. Hudson, and Paulo E. Arratia*, Three-dimensional structures and symmetry breaking in viscoelastic cross-channel flow, Soft Matter 16, 6969-6974 (2020). *: Co-corresponding author. † Featured as journal cover.
Boyang Qin*, Paul F. Salipante, Steve D. Hudson, and Paulo E. Arratia*, Upstream vortex and elastic wave in the viscoelastic flow around confined cylinder, J. Fluid Mech. 864, R2 (2019). *: co-corresponding author.
Boyang Qin and Paulo E. Arratia, Characterizing elastic turbulence in channel flows at low Reynolds number, Phys. Rev. Fluids 2, 083302 (2017).
国家自然科学基金优秀青年科学基金项目 (海外)，主持，2024年1月 - 2026年12月。
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