Huang Kai

Selected Publications

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    Ren H, Hu W, Jiang T, Yao Q, Qi Y, Huang K. Mechanical stress induced mitochondrial dysfunction in cardiovascular diseases: Novel mechanisms and therapeutic targets. Biomedicine & Pharmacotherapy. 2024; 174, 116545. (通讯作者). JCR Q1

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    Huang K*, Wu Y*, Zhang Y, Youn JY, Cai H. Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication. Redox Biology. 2022; 58:102521. 中科院一区TOP

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    Huang K*, Narumi T*, Zhang Y, Li Q, Murugesan P, Wu Y, Liu NMJ, Cai H. Targeting miR-192-5p, a downstream effector of NOXs, reverses endothelial dihydrofolate reductase deficiency to attenuate abdominal aortic aneurysm formation. Hypertension. 2021;78(2):282-293. 中科院一区TOP

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    Huang K*, Zhang P*, Zhang Z*, Youn JY*, Wang C, Zhang H, Cai H. Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and viral infections: Efficacies and mechanisms. Pharmacology & Therapeutics. 2021;225:107843. ESI Highly Cited Paper 中科院一区TOP

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    Huang K*, Wang Y*, Siu KL*, Zhang Y, Cai H. Targeting feed-forward signaling of TGFβ/NOX4/DHFR/eNOS uncoupling/TGFβ axis with anti-TGFβ and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics. Redox Biology. 2021;38:101757. 中科院一区TOP

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    Huang K, Bao H, Yan ZQ, Wang L, Zhang P, Yao QP, Shi Q, Chen XH, Wang KX, Shen BR, Qi YX, Jiang ZL. MicroRNA-33 protects against neointimal hyperplasia induced by arterial mechanical stretch in the grafted vein. Cardiovascular Research. 2017, 113(5):488-497. (Cover Article & Editor Choice & Editorial; High impact Cardiovascular Research; Recent Cardiovascular Research highlights from China). 中科院一区TOP

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    Jiang J, Huang K, Xu S, Garcia JGN, Wang C, Cai H. Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction. Redox Biology. 2020 ;36:101638. 中科院一区TOP

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    Zhang Y, Murugesan P, Huang K, Cai H. NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets. Nature Reviews Cardiology. 2020 Mar; 17(3):170-194. ESI Highly Cited Paper 中科院一区TOP

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    Qi YX, Yao QP, Huang K, Shi Q, Zhang P, Wang GL, Han Y, Bao H, Wang L, Li HP, Shen BR, Wang Y, Chien S, Jiang ZL. Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application. Proc Natl Acad Sci U S A (PNAS). 2016, 113(19):5293-5298. 中科院一区TOP

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    Youn JY, Middlekauff HR, Reudiseuli I, Huang K, Cai H. Endothelial damage in young adult e-cigarette users. Redox Biology. 58 (2023) 102688. 中科院一区TOP