Sun Donglei

Tenure-track Associate Professor

  • Tel: 021-34208469
  • Email: dongleisun@sjtu.edu.cn
  • Address:
  • Lab Web: life.sjtu.edu.cn/teacher/dongleisun
  • My research focuses on the immunology and immunopathology during infection and major diseases. Special interest is the role of monocyte/macrophage cell lineages in these scenarios. My expertise is the use of different imaging techniques (intravital microscopy, live-cell imaging, etc.) to study monocyte/macrophage behavior and functions.

Selected Publications

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    Sun D*, Zhang M*, Sun P, Liu G, Strickland AB, Chen Y, et al.. VCAM1/VLA4 interaction mediates Ly6Clow monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection. PLoS Pathogens 2020 16(2): e1008361.

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    Sun D*, Sun P*, He S, Shi M. Rat IgG mediated circulatory cell depletion in mice requires mononuclear phagocyte system and is facilitated by complement. Journal of Leukocyte Biology. 2020 107:529–539.

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    Sun DL*, Gao YZ*, Ge X*, Shi ZL, Zhou NY. Special features of bat microbiota differ from those of terrestrial mammals. Frontiers in Microbiology. 2020 11:1040.

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    Sun D, Sun P, Li H, Zhang M, Liu G, Strickland AB et al.. Fungal dissemination is limited by liver macrophage filtration of the blood. Nature Communications 2019 10 (1), 1-14. (F1000 Recommended)

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    Liu G, Fu Y, Yosri M, Chen Y, Sun P, Xu J, Zhang M, Sun D et al.. CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement Proceedings of the National Academy of Sciences 2019 116 (48), 24214-24220.

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    Sun D, Zhang M, Liu G, Wu H, Li, Zhou H, Zhang X, Shi M. Intravascular clearance of disseminating Cryptococcus neoformans in the brain can be improved by enhancing neutrophil recruitment in mice. European Journal of Immunology 2016 46(7):1704-1714.

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    Zhang M*, Sun D*, Liu G, Wu H, Zhou H, Shi M. Real-time in vivo imaging reveals the ability of neutrophils to remove Cryptococcus neoformans directly from the brain vasculature. Journal of Leukocyte Biology. 2016 99(3):467-473.

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    Sun D, Zhang M, Liu G, Wu H, Zhu X, Zhou H, Shi M. Real-time imaging of interactions of neutrophils with Cryptococcus neoformans demonstrates a crucial role of complement C5a-C5aR signaling. Infection and Immunity. 2015 84(1):216-229.

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    Sun D, Shi M. Neutrophil swarming toward Cryptococcus neoformans is mediated by complement and leukotriene B4. Biochemical and Biophysical Research Communications. 2016 477(4):945-951

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    Sun DL, Jiang X, Wu QL, Zhou NY. Intragenomic heterogeneity of 16S rRNA genes causes overestimation of prokaryotic diversity. Applied Environmental Microbiology. 2013 79(19):5962-9.