Zhang F^#, Zhang F^#, Yu XC^#, Sun RZ, Wu YZ, Zhou YW, Li L*. Discovery of a novel family of Gram-negative-active cationic cyclolipopeptides by motif search-guided chemical synthesis. CCS Chemistry 2024; doi: 10.31635/ccschem.024.202404925.

Sun RZ^#, Zhao D^#, Yu XC^#, Zhang F, You RX, Luo XX, Li L*. Discovery of a family of menaquinone-targeting cyclic lipodepsipeptides for multidrug-resistant Gram-positive pathogens. Communications Biology 2024; 7:1453. 

Sun RZ, You RX, Yu XC, Zhao D, Li L*. Discovery and synthesis of a Gram-negative-active cationic lipopeptide antibiotic inspired by primary sequences from underexplored Gram-negative bacteria. Organic Letters 2024; 26:1348-1352.

Li L*. Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery. Biotechnology Advances 2023; 66:108176.

Li L, Koirala B, Hernandez Y, MacIntyre LW, Russo R, Ternei MA, Brady SF*. Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens. Nature Microbiology 2022; 7:120-131.

Li L, Wei KK, Liu XC, Wu YJ, Zheng GS, Chen SX, Jiang WH*, Lu YH*. aMSGE: advanced multiplex site-specific genome engineering with orthogonal modular recombinases in actinomycetes. Metabolic Engineering 2019; 52:153-167.

Li L, Liu XC, Wei KK, Lu YH*, Jiang WH*. Synthetic biology approaches for chromosomal integration of genes and pathways in industrial microbial systems. Biotechnology Advances 2019; 37(5):730-745.

Li L, Zheng GS, Chen J, Ge M, Jiang WH*, Lu YH*. Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes. Metabolic Engineering 2017; 40:80-92.

Li L, Jiang WH*, Lu YH*. New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products. Biotechnology Advances 2017; 35:936-949.

Li L, Zhao YW, Ruan LJ, Yang S, Ge M, Jiang WH*, Lu YH*. A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering. Metabolic Engineering 2015; 29:12-25.