Dongqing Wei

Tenured Professor

  • Tel: +86-021-34204573
  • Email: dqwei@sjtu.edu.cn
  • Lab Web: tacc2008.sjtu.edu.cn
  • Tenured professor, FRSC, Editor-In-Chief, Interdisciplinary Sciences – Computational Life Sciences, a highly cited scholar, published 700 papers with more than 18000 citations, a H-index 72, H10-index 360. Made many ground breaking contributions to science.
DOWNLOAD CV

Education and Research Experience

  • 1987 – 1990  Post-doctoral Fellow, Department of Chemistry, University of British Columbia, Vancouver, B.C., Canada, with Gren Patey.
  • 1985 – 1987  Ph.D., Chemical Physics Program at the Department of Physics, University of Puerto Rico, Rio Piedras, Puerto Rico, USA, thesis supervisor: Lesser Blum.
  • 1982 – 1985   M.S., Department of Chemistry, Normal University of Henan, Xinxiang, Henan, People's Republic of China.
  • 1978 – 1982   B.S., Department of Chemistry, Normal University of Henan, Xinxiang, Henan, People's Republic of China.
  • Academic and Research Positions
  • 2006 – Present, Tenured Professor (长聘教授) at the State Key Laboratory of Microbial of Metabolism & Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China; an external member at Centre for Research in Molecular Modeling (CERMM), Concordia University in Montreal, Canada; and Adjunct Professor at Pengcheng National Lab.
  • 2003-2006, The Haihe Distinguished Professor, appointed by the City of Tianjin at Tianjin Normal University, Directory General, Tianjin Institute of Bioinformatics and Drug Discoveries, Principal Scientist, Gordon Life Science Institute, San Diego, USA, and an external member at Centre for Research in Molecular Modeling (CERMM), Concordia University in Montreal, Canada.
  • 1993 - 2003, Research Scientist, Centre de Recherche en Calcul Applique (CERCA, Research Center on Computation and its Application), Montreal, Quebec.
  • 1990 - 2000, Professor of Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing, P.R. China.
  • 1990 – 1992, Research Associate, Department of Chemistry, University of British Columbia, Vancouver, BC., Canada, with Gren Patey.
  • 1985 – 1985, Assistant Professor, Department of Chemistry, Normal University of Henan, Xinxiang, Henan, People’s Republic of China.

Selected Publications

  • •  

    Cited 98 times -Jing Chang, Peng Lian, Dong-Qing Wei*, Xiang-Rong Chen, Zizheng Gong and Qingming Zhang, “Thermal decomposition of the solid phase of nitromethane: Ab initio molecular dynamics simulations”, Phys. Rev. Lett. 105, 188302 -188305(2010).

    PDF SUPP INOF
    •  

    Cited 40 times -Ruo-Xu Gu, Limin Angela Liu*, and Dong-Qing Wei*, “Free Energy Calculations on the Two Drug Binding Sites in the M2 Proton Channel”, J. Am. Chem. Soc., 133 (28), 10817–10825(2011).

    PDF SUPP INOF
    •  

    Cited 61 times - Maoping Tang, Zhaoxia Wang, Ying Zhou, Wangjie Xu, Shengtian Li,Lianyun Wang, Dong-Qing Wei*, Zhongdong Qiao*, “A novel drug candidate for Alzheimer disease treatment - gx-50 derived from Zanthoxylum Bungeanum”, J. Alzheimer’s Disease, 34, 203–213 (2013).

    PDF SUPP INOF
    •  

    (Cited 341 times) Wei, D. and G. Patey, "Orientational order in simple dipolar liquids: computer simulation of a ferroelectric nematic phase". Physical review letters, 1992. 68(13): p. 2043-2045.

    PDF SUPP INOF
    •  

    (Cited 180 times) Wei, D. and D. Salahub, "Hydrated proton clusters and solvent effects on the proton transfer barrier: A density functional study". The Journal of chemical physics, 1994. 101(9): p. 7633-7642.

    PDF SUPP INOF
  • •  

    (Cited 139 times) Chu, Y., A.C. Kaushik, X. Wang, W. Wang, Y. Zhang, X. Shan, D.R. Salahub, Y. Xiong, and Wei D.Q., "DTI-CDF: a cascade deep forest model towards the prediction of drug-target interactions based on hybrid features". Briefings in Bioinformatics, 2019, doi: 10.1093/bib/bbz152.

    PDF SUPP INOF
    •  

    (Cited 131 times) Wang, C., Wang, S., Li, D., Wei, D.Q.*, Zhao, J*. and Wang, J.*, “Human intestinal defensin 5 inhibits SARS-CoV-2 invasion by cloaking ACE2”. Gastroenterology, 2020, DOI: 10.1053/j.gastro.2020.05.015.

    PDF SUPP INOF
    •  

    (Cited 121 times)  Chu, Y., Zhang, Y., Wang , Q.K., Zhang, L.F.,  Wang, X.H., Wang, Y.J., , Salahub, D.R., Xu, Q.., Wang, J.M., Jiang,  X., Xiong, Y*,  and Wei, D.Q.*,  “A transformer-based model to predict peptide–HLA class I binding and optimize mutated peptides for vaccine design”,  Nature Machine Intelligence, 2022, 4(3):300-311, DOI: 10.1038/s42256-022-00459-7 (2021).

    PDF SUPP INOF