9-29 Complexity Generation in Fungal Natural Product Biosynthesis

微生物代谢国家重点实验室学术交流会暨国重实验室科技创新训练课程

SKLMM Workshop  (Presentation in English)

 

报告题目:Complexity Generation in Fungal Natural Product Biosynthesis

报 告  人:Yi Tang  Chancellor Professor

Department of Chemical and Biomolecular Engineering, UCLA

Director, NIH Predoctoral Biotechnology Training Grant

会议时间:9月29日(星期五) 14:00-15:30

会议地点:闵行校区文选医学大楼1楼报告厅

主 持  人:白林泉 教授

联 系  人:林忆杉 This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

 

报告摘要:

Nature performs challenging synthetic transformations using powerful enzymes.  These enzymes are frequently found in the biosynthetic pathways of natural products, many of which have served as inspirations for generations of synthetic chemists over the last fifty years.  With recent advances in our abilities to manipulate the biosynthetic pathways, many powerful enzymes have been revealed and characterized.  In this talk, I will present a selection of recent work in the identification, characterization and engineering of several enzymes that catalyze difficult transformations and generate structural complexity in fungi.  Examples include multifunctional P450s, Diels Alderases and enzymes that catalyze epoxide rearrangements will be covered.

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