张晓君 的个人介绍页
张晓君
张晓君
研究员
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个人简历

1990年和1995年在兰州大学生物系分别获学士和硕士学位;
2002年在中科院寒区旱区环境与工程研究所获得博士学位;
1995年-1999年,在兰州大学生物系任教(讲师);
2002年-2004年挪威农业大学(现挪威生命科学大学)化学与生物技术系博士后;
2004年9月开始在上海交通大学生命学院微生物分子生态学与基因组学实验室任副教授,2013年开始任研究员。
2006年-2007年在法国里昂第一大学微生物生态学实验室(UMR CNRS 5557)访问研究。
2006年起担任中国微生物学会环境微生物专业委员会委员,上海市微生物学会环境微生物专业委员会委员。现任上海市微生物学会常务理事、副秘书长。《微生物学通报》、《Applied Environmental Biotechnology》编委, PLoS ONE、Research in Microbiology等国际SCI刊物及国内多个核心期刊的审稿人。

研究方向

1. 微生物群落的分子生态学与生态基因组学;
2. 有机污染物反硝化降解菌群结构和功能关系研究;
3. 农田土壤系统中反硝化菌群与氮循环关系研究。
涉及工业废水微生物处理过程微生物群落结构与功能分析、功能菌分离、功能基因的克隆、元基因组学、以及农业土壤环境的分子生态学、石油油藏微生物分子分析等方面的研究。

发表论文

1.Chenhong Zhang, Aihua Yin, Hongde Li, Ruirui Wang, Guojun Wu, Jian Shen, Menghui Zhang, Linghua Wang, Yaping Hou, Haimei Ouyang, Yan Zhang, Yinan Zheng, Jicheng Wang, Xiaofei Lv, Yulan Wang, Feng Zhang, Benhua Zeng, Wenxia Li, Feiyan Yan, Yufeng Zhao, Xiaoyan Pang, Xiaojun Zhang, Huaqing Fu, Feng Chen, Naisi Zhao, Bruce R. Hamaker, Laura C. Bridgewater, David Weinkove, Karine Clement, Joel Dore, Elaine Holmes, Huasheng Xiao, Guoping Zhao, Shengli Yang, Peer Bork, Jeremy K. Nicholson, Hong Wei, Huiru Tang, Xiaozhuang Zhang, Liping Zhao, Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children,EBioMedicine, 2015, 8(2):968-984, doi:10.1016/j.ebiom.2015.07.0
2.Xu Zhang, Yufeng Zhao, Jia Xu, Zhengsheng Xue, Menghui Zhang, Xiaoyan Pang, Xiaojun Zhang, and Liping Zhao. Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats. Scientific Report, 2015, 5, 14405; doi: 10.1038/srep1440
Zhengsheng Xue, Wenping Zhang, Linghua Wang, Rong Hou, Menghui Zhang, Lisong Fei, Xiaojun Zhang, He Huang, Laura C. Bridgewater, Yi Jiang, Chenglin Jiang, Liping Zhao, Xiaoyan Pang, Zhihe Zhang. The bamboo-eating giant panda harbors a carnivore-like gut microbiota, with excessive seasonal variations. mBio. 2015, 6(2):e00022-15. DOI:10.1128/mBio.00022-15
3.Ren H, Gao G, Song Z, Wang W, Zhao L, Zhang X* Bacteria in the injection water differently impacts the bacterial communities of production wells in high-temperature petroleum reservoirs. Frontiers in Microbiology, 2015; 6:505. DOI:10.3389/fmicb.2015.00505
4.Shunzi Xiong,Xia Li, Jianfa Chen, Liping Zhao, Hui Zhang, Xiaojun Zhang*. Crude oil degradation by bacterial consortia under four different redox and temperature conditions. Applied Microbial and Biotechnology, 2014,99(3): 1451-1461. Doi:10.1007/s00253-014-6042-7.
5.Fei Huang, Ling Ge, Bo Zhang, Yun Wang, Hao Tian, Liping Zhao, Yiliang He, Xiaojun Zhang*. A fullerene colloidal suspension stimulates the growth and denitrification ability of wastewater treatment sludge derived bacteria. Chemosphere, 2014,108:411–417.
6.Shuiming Xiao, Na Fei, Xiaoyan Pang, Jian Shen, Linghua Wang, Baorang Zhang, Menghui Zhang, Xiaojun Zhang,Chenhong Zhang, Min Li, Lifeng Sun, Zhengsheng Xue, Jingjing Wang, Jie Feng, Feiyan Yan, Naisi Zhao, Jiaqi Liu, Wenmin Long, Liping Zhao. A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome, FEMS Microbiology Ecology, 2014, 87(2):357-67. doi: 10.1111/1574-6941.12228.
7.Yuze Song, Pan Yu, Bailin Li, Yingjie Pan, Xiaojun Zhang, Jian Cong, Yinying Zhao, Hua Wang and Lanming Chen . The mosaic accessory gene structures of the SXT/R391-like integrative and conjugative elements derived from Vibriospp. isolated from aquatic products and environment in the Yangtze River estuary,China. BMC Microbiology 2013, 13:214. doi:10.1186/1471-2180-13-214
8.Jie Feng, Huang Tang, Min Li, Xiaoyan Pang, Linghua Wang, Menghui Zhang, Yufeng Zhao, Xiaojun Zhang, Jian Shen*.The abundance of fecal Faecalibacterium prausnitzii in relation to obesity and gender in Chinese adults. Archives of Microbiology, 2013, 196(1):73-7. DOI 10.1007/s00203-013-0942
9.Zhang X *, Jeseph Nesme, Pascal Simonet and ?sa Frosteg?rd. Fate of invading bacteria in soil and survival of transformants after simulated uptake of transgenes, as evaluated by a model system based on lindane degradation. Research in Microbiology, 2012, 163:200-210. 10.1016/j.resmic.2012.01.007
10.Xie B, Xiong S, Liang S, Hu C, Zhang X, Lu J.. Performance and bacterial compositions of aged refuse reactors treating mature landfill leachate. Bioresource Technology, 2012, 103:71-77. (Joint first authors)
11.Xu W., Huang Z., Zhang X., Li Q., Lu Z., Shi J., Xu Z., Ma Y. Monitoring the microbial community during solid-state acetic acid fermentation of Zhenjiang aromatic vinegar. Food Microbiology, 2011, 28(6):1175-1181
12.Ren H, Zhang X*, Song Z, Rupert W, Gao G, Guo S, Zhao L. Comparison of Microbial Community Compositions of Injection and Production Well Samples in a Long-term Water-Flooded Petroleum Reservoir. PLoS One, 2011,6(8): e23258. doi:10.1371/journal.pone.0023258
13.Zhang X*,Yue S, Zhong H, Hua W, Chen R, Cao Y, and Zhao L. A diverse bacterial community in an anoxic quinoline-degrading bioreactor determined by using pyrosequencing and clone library analysis. Applied Microbial and Biotechnology, 2011, 91:425?434.
14.Wang Tingting, Zhang Xiaojun*, Zhang Menghui, Wang Linghua, Zhao Liping. Development of a fluorophore-ribosomal DNA restriction typing method for monitoring structural shifts of microbial communities. Archives in Microbiology, 2011, 193:341?350.
15.Lu, H., Wu, W., Chen, Y., Zhang, X., Devare, M., Thies, J.E. Decomposition of Bt transgenic rice residues and response of soil microbial community in rape seed-rice cropping system. Plant and Soil, 2010, 336:279-290. (SCI IF:2.517)
16.Hong X, Zhang X*, Liu B, Mao Y, Liu Y, and Zhao L. Structural differentiation of bacterial communities in indole-degrading bioreactorsunder denitrifying and sulfate-reducing conditions . Research in Microbiology, 2010,161(8): 687-693. (SCI IF:2.154)
17.Mao Y, Zhang X*, Xia X, Zhong H, Zhao L. Versatile aromatic compound-degrading capacity and microdiversity of Thauera strains isolated from a coking wastewater treatment bioreactor. J Ind Microbiol Biotechnol. 2010,37:927-934. (SCI IF:1.798)
18.Zhang C, Zhang M, Wang S, Han R, Cao Y, Hua W, Mao Y, Zhang X, Pang X, Wei C, Zhao G, Chen Y, Zhao L.. Interactions between gut microbiota, host genetics, and diet relevant to development of metabolic syndromes in mice. ISME J, 2010, 4(2): 232-241. (SCIIF:5.039)
19.Wang L., Jin Y., Zhao L. , Pang X. and Zhang X*. ERIC-PCR-based strain-specific detection of phenol-degrading bacteria in activated sludge of wastewater treatment systems. Letters in Applied Microbiology, 2009, 49:522-528 (SCI IF:1.68)
20.Zhang X, Ma X, Wang N, Yao T. New subgroup of Bacteroidetes and diverse microorganisms in Tibetan plateau glacial ice provide a biological record of environmental conditions. FEMS Microb. Ecol., 2009, 67:21-29. (SCI IF:3.039)
21.Mao Y, Zhang X*, Yan X, Liu B, Zhao L. Development of group-specific PCR-DGGE fingerprinting for monitoring structural changes ofThauera spp. in an industrial wastewater treatment plant responding to operational perturbations. J Microbiol Methods. 2008, 75: 231?236. (SCI IF:2.153)
22.Yang C, Cao G, Li Y, Zhang X, Ren H, Wang X, Feng J, Zhao L, Xu P. A Constructed Alkaline Consortium and Its Dynamics in Treating Alkaline Black Liquor with Very High Pollution Load. Plos One, 2008, 3(11):e3777. 2008,20. doi:10.1371/journal.pone.0003777(SCI IF: 4.351)
23.Wang H, Zhang X, Zhao L, Xu Y. Analysis and comparison of the bacterial community in fermented grains during the fermentation for two different styles of Chinese liquor. J Ind Microbiol Biotechnol., 2008, 35:603?609. (SCI IF: 1.681)
24.Yan X, Z Xu, X Feng, Y Liu, B Liu, X Zhang, C Zhu, L Zhao. Cloning of Environmental Genomic Fragments as Physical Markers for monitoring Microbial populations in Coking Wsatewater Treatment System. Microbial Ecology. 2007,53:163-172. (SCI IF:2.558)
25.Liu B, Zhang F, Feng X, Liu Y, Yan X, Zhang X, Wang L, Zhao L. Thauera and Azoarcus as Functionally Important Genera in a Denitrifying Quinoline Removal Bioreactor as Revealed by Microbial Community Structure Comparison. FEMS Microbiology Ecology, 2006, 55 (2): 274-286. (SCI IF:3.039)

研究成果

主要从事环境微生物生态学的研究工作。先后主持两项国家自然科学基金项目和863重点项目子课题、上海市国际合作项目、上海市农委重点攻关项目、教育部回国留学人员启动基金等科研项目,还承担国家自然科学基金重点项目合作研究及其它横向课题。开展了对焦化废水这一难降解工业废水的微生物群落的深入研究,通过以喹啉反硝化降解反应器为模型揭示了菌群结构和特定基因组成及其变化规律;特别关注Thauera属细菌这类重要的污染物分解菌,创建了一套分析Thauera属细菌的方法,为研究重要降解功能菌奠定了良好基础;在分子标识物引导的群落内关键菌群的分离技术方面有所创新,并分离了一批反硝化降解菌,研究了这些降解菌的特性。与挪威农业大学合作研究农田土壤系统中反硝化菌群与氮循环关系,揭示了反硝化基因表达与调控机制。还对油藏极端环境的微生物生态学开展了探索研究,提出一些独特的观点。近年来在国内外刊物上发表论文80余篇,其中SCI论文30余篇。获上海交通大学晨星学者、优秀教师等奖励。
个人学术链接:https://www.researchgate.net/profile/Xiaojun_Zhang8