上海交通大学特别研究员、博士生导师。2009年1月获韩国科学技术院(KAIST) 生命化学工学科博士学位，先后在韩国KAIST及美国Tufts大学从事博士后研究。 2012年9月被聘为上海交通大学特别研究员、博士生导师。主要从事系统与合成生物学的研究，尤其致力于其在生物材料、绿色化工和能源等领域的应用基础研究。在国际重要学术刊物上发表论文十多篇，其中包括PNAS，Biotechnology & Bioengineering等高水平国际期刊。所发表的论文被选为Nature 杂志的Research Highlight， Nature Chemical Biology 的News and Views，Biotechnology & Bioengineering 的封面、亮点文章和Editors’ Choice。 研究成果已申请三个国际专利和数个韩国专利。被邀请为 Biotechnology & Bioengineering，Biomacromolecules等五个国际杂志的论文审稿人。

• 先进材料的仿生合成
• 新型智能生物材料的设计与合成
• 蛋白生物材料的高效生物制造及应用

1. Huang SC†, Qian ZG†, Dan AH, Hu X, Zhou ML, Xia XX*. Rational design and hierarchical assembly of a genetically engineered resilin-slik copolymer results in stiff hydrogels. ACS Biomater Sci Eng 2017 (in press)
2. Chen L, Zhou ML, Qian ZG, Kaplan DL, Xia XX*. Fabrication of protein films from genetically engineered silk-elastin-like proteins by controlled cross-linking. ACS Biomater Sci Eng 2017, 3(3):335-341.
3. Zhou ML, Qian ZG, Chen L, Kaplan DL, Xia XX*. Rationally designed redox-sensitive protein hydrogels with tunable mechanical properties. Biomacromolecules 2016, 17(11): 3508-3515.
4. Peng Q, Zhang Y*, Lu L, Shao H, Qin K, Hu X, Xia X*. Recombinant spider silk from aqueous solutions via a bio-inspired microfluidic chip. Sci Rep, 2016, 6, 36473.
5. Qin N, Zhang S, Jiang J, Corder SG, Qian Z, Zhou Z, Lee W, Liu K, Wang X, Li X, Shi Z, Mao Y, Bechtel HA, Martin MC, Xia X, Marelli B, Kaplan DL, Omenetto FG, Liu M, Tao TH. Nanoscale probing of electron-regulated structural transitions in silk proteins by near-field IR imaging and nano-spectroscopy. Nat Commun, 2016, 7:13079.
6. Huang W, Tarakanova A, Dinjaski N, Wang Q, Xia X, Chen Y, Wong JY, Buehler MJ, Kaplan DL. Design of multistimuli responsive hydrogels using integrated modeling and genetically engineered silk-elastin-like-proteins. Adv Funct Mater, 2016, 26(23):4113-23.
7. Yang YX, Qian ZG, Zhong JJ*, Xia XX*. Hyper-production of large proteins of spider dragline silk MaSp2 by Escherichia coli via synthetic biology approach. Process Biochem 2016, 51(4): 484-490.
8. Qian ZG†, Zhou ML†, Song WW, Xia XX*. Dual thermosensitive hydrogels assembled from the conserved C-terminal domain of spider dragline silk. Biomacromolecules, 2015, 16(11):3704–3711.
9. Yu JL, Xia XX, Zhong JJ*, Qian ZG*. Direct biosynthesis of adipic acid from a synthetic pathway in recombinant Escherichia coli. Biotechnol Bioeng, 2014, 111(12):2580-2586.
10. Qi K, Zhong JJ*, Xia XX*. Triggering respirofermentative metabolism in the Crabtree-negative yeast Pichia guilliermondii by disrupting the CAT8 Gene. Appl Environ Microbiol 2014, 80(13):3879-3887 (Co-corresponding authors)
11. Wang Q†, Xia X†, Huang W, Lin Y, Xu Q, Kaplan DL*. High throughput screening of dynamic silk-elastin-like protein biomaterials. Adv Funct Mater, 2014, 24(27):4303-4310 (†Co-first authors)
12. Lin Y†, Xia XX†, Wang M†, Wang Q, An B, Tao H, Xu Q, Kaplan DL*. Genetically programmable thermoresponsive plasmonic gold/silk-elastin protein core/shell nanoparticles. Langmuir, 2014, 30(15):4406-4414 (†Co-first authors)
13. Xia XX†, Wang M†, Lin Y, Xu Q, Kaplan DL*. Hydrophobic drug-triggered self-assembly of nanoparticles from silk-elastin-like protein polymers for drug delivery. Biomacromolecules, 2014, 15(3):908-914. (†Co-first authors)
14. Lin Y, Xia X, Shang K, Elia R, Huang W, Cebe P, Leisk G, Omenetto F, Kaplan DL*. Tuning chemical and physical cross-links in silk electrogels for morphological analysis and mechanical reinforcement. Biomacromolecules, 2013, 14(8):2629–2635.
15. Fan C, Qi K, Xia XX*, Zhong JJ*. Efficient ethanol production from corncob residues by repeated fermentation of an adapted yeast. Bioresource Technol, 2013, 136:309-315. (co-corrsponding author)
16. Sun Z, Qin G, Xia X, Mark, CG, Omenetto, F, Kaplan DL*. Photoresponsive retinal-modified silk-elastin copolymer. J Am Chem Soc, 2013, 135 (9): 3675–3679.
17. Xia XX, Xu Q, Hu X, Qin G, Kaplan DL*. Tunable self-assembly of genetically engineered silk-elastin protein polymers. Biomacromolecules, 2011, 12(11):3844-3850.
18. Xia XX, Qian ZG, Ki CS, Park YH, Kaplan DL, Lee SY*. Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci USA, 2010, 107(32):14059-14063.
19. Qian ZG†, Xia XX†, Lee SY*. Proteome-based identification of fusion partner for high-level extracellular production of recombinant proteins in Escherichia coli. Biotechnol Bioeng, 2008, 101(3):587-601. (†equal contribution)
20. Xia XX, Han MJ, Lee SY*, Yoo JS. Comparison of the extracellular proteomes of Escherichia coli B and K-12 strains during high cell density cultivation. Proteomics, 2008, 8(1): 2089-2103.